What is alpha yohimbine (rauwolscine)
Alpha Yohimbine (rauwolscine), according to the definition of from wikipedia, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauwolfia and Pausinystalia (formerly known as Corynanthe).It is a stereoisomer of yohimbine.Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac.
Rauwolscine acts predominantly as a α2-adrenergic receptor antagonist. It has also been shown to function as a 5-HT1A receptor partial agonist and 5-HT2A and 5-HT2B receptor antagonist.
Rauwolscine is what is known as a diastereoisomers of Yohimbine. There are 3 diastereoisomers, the other two being corynanthine and 3-epi-alpha-yohimbine. Basically, it is an alternate form of it with slightly altered properties.
It's mechanisms of action are very similar to yohimbine, as it can act as an Alpha(2)Adrenergic antagonist and thus aid in fat burning (not so much by inducing fat loss, but by alleviating pressures the body exerts to preserve fat mass; its like preventing the body from stopping the fat loss, but doesn't induce it directly). Rauwolscine shows some promise in being more effective due to higher potency on the same receptor.
It also shares the same aphrodisiac and mood-elevating effects as yohimbine, although the potency on this relative to yohimbine is not known.
What’s the difference between alpha yohimbine and yohimbine hcl?
These two ingredients are quite different.
1. The CAS numbers are different. The CAS of alpha yohimbine is 6211-32-1 while that of yohimbine hcl is CAS 65-19-0. These physical features shows they are not the same.
2. Alpha yohimbine is said to be healthier more potent than yohimbine. Rauwoliscine is alpha-yohimbine, an analogue of yohimbine. Rauwoliscine amplifies energy levels and supports the body's fat-burning process. Alpha-yohimbine has a more targeted effect than yohimbine without the side effects.
3. The price differs greatly. The price of alpha yohimbine is 6-8 times higher than normal yohimbine 98%.
Health Benefits of alpha yohimbine (rauwolscine)
Benefits of taking Alpha Yohinbine (rauwoliscine) supplements:
1. Fat-Burning Potential Rauwolscine is a potent and selective antagonist of alpha-2 adrenergic receptors. rauwolscine (alpha-yohimbine): a specific antagonist radioligand for brain alpha 2-adrenergic receptors. This is the same mechanism by which yohimbine acts.
2. Blood Vessel and Cardiac Health {3H}Rauwolscine is less potent than Yohimbine in protecting against adrenaline-induced blood pressure increases (both of which were less potent than corynanthine and more potent than 3-epi-alpha-yohimbine), this effect seems related to their affinity for the alpha-2 adrenoreceptor.
3. Serotonergic Effects Like yohimbine, rauwolscine is an agonist of 5-HT1a/b receptors and induce serotonin-like effects. While yohimbine has more affinity for the receptor, rauwolscine has a lower IC50 value (meaning it can saturate more receptors at the same dose) and can be seen as slightly more potent in serotonergic activity
