What is 7,8-dihydroxyflavone?
7,8-dihydroxyflavone also called 7,8-DHF. 7,8-dihydroxyflavone (7,8-DHF) is a compound flavonoid that was firstly discovered a study for small molecules that could activate a particular receptor known as tropomyosin-related kinase B (TrkB), because the peptide produced in the human body that acts on this receptor, called brain derived nootropics factor , could not be used due to poor absorption into the brain. 7,8-DHF is both orally-bioavailable and able to penetrate the blood-brain-barrier,[7] though with a relatively short half-life.
How its works?
7,8-dihydroxyflavone (7,8-DHF) was found to be a potent mimic of BDNF able to act on TrkB in a similar manner. This means that 7,8-DHF could theoretically cause similar effects as BDNF in the brain, and in theory be more therapeutically useful due to its better absorption and ability to cross the blood-brain barrier. Recently the authority reported that 7,8-dihydroxyflavone (7,8-DHF) can benefit body healthy. It can improve brain memory and cognitive enhancement. In addition, it has been found to inhibit aldehyde dehydrogenase and estrogen sulfotransferase. Also 7,8-dihydroxyflavone (7,8-DHF) can make people concentrate on their concentrations. Make people have good sleep and mood.
Dosage and recommend
Studies conducted to evaluate effects of 7,8-dihydroxyflavone (7,8-DHF) revealed that 40 to 80 mg daily is effective in treating depression and cognitive symptoms amongst healthy patients.
